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What is Restylane?
Restylane is a safe and natural
cosmetic dermal filler that restores
volume and fullness to the skin to
correct moderate to severe facial
wrinkles and folds, such as
nasolabial folds.
Is Restylane
safe?
Yes. Restylane has
been used safely by dermatologists
and plastic surgeons since 1996
worldwide. Because Restylane is
non-animal-based and fully
biocompatible, allergy testing is not
required. There is virtually no risk
of animal-based disease transmission
or allergic reaction. The most
commonly reported side effects were
temporary redness and swelling at the
injection site. These effects
typically resolve within two to three
days.
How is
Restylane different from Botox?
Restylane is a
natural cosmetic filler. In contrast,
Botox is a drug that blocks nerve
transmission and relaxes the
underlying muscles. Many patients
have been very pleased after
receiving treatment with both
products.

What is Restylane made of?
Restylane is the
first and only cosmetic dermal filler
made of non-animal-based hyaluronic
acid. Hyaluronic acid is a natural
substance that already exists in the
human body and is used to provide
volume and fullness to the skin. The
hyaluronic acid in Restylane is a
crystal-clear gel called NASHA, or
Non-Animal Stabilized Hyaluronic
Acid. NASHA is biodegradable and
completely biocompatible with human
hyaluronic acid.
How is Restylane different
than other hyaluronic acid-based
products?
Unlike other
hyaluronic acid-based products, such
as those made from rooster combs,
only Restylane is non-animal-based.
This quality virtually eliminates any
risk of animal-based disease
transmission or allergic reaction.
How long does Restylane last?
Studies have shown
that the average treatment results
last up to six months or even longer.
The unique NASHA™ technology helps
maintain the cosmetic effect until
the injected material is nearly gone.
Now that you have the answers
to some important questions, why
wait?
If you want to enjoy
a smoother, more youthful appearance
for up to six months, or even longer,
ask your
physician if Restylane is right
for you. The simple procedure can be
done during your lunch hour. And the
effects are immediate.
Restylane compared to other
treatments:
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Description |
Procedure |
Safety |
Duration |
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Botulinum Toxin Type A |
Botulinum
Toxin Type A is a toxin
that blocks neuromuscular
transmission when injected
in tiny amounts into
specific muscles to treat
and improve lines and
wrinkles associated with
facial expression.
Manufactured under the
names of Botox© and Dysport©
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Botulinum
toxin is injected in minute
quantities. It blocks the
nerve impulses to the
facial muscles responsible
for contraction, thereby
relaxing the muscles and
smoothing facial lines. It
is most effective on frown
lines and crow's feet
around the eyes. Accurate
dosing and precise
positioning are critical in
order to freeze the right
muscles just enough.
The
treatment takes about 30
minutes and the effect of a
treatment can be seen
within 1 - 2 weeks.
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The
long-term risks of
botulinum toxin are
unknown. Redness may occur,
as well as bruising,
numbness, swelling and
headaches. If overdosed or
the injection is performed
incorrectly, the patient
can be left with an
immobile face or droopy
eyelids until the effect of
the injection wears off. |
The result
lasts for about four
months. |
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Collagen treatment |
Collagen is
derived from the hides of
cows specially bred for the
purpose. Collagen can also
be derived from pig skin.
Because collagen is an
animal product, a collagen
test skin implant is
administered to determine
whether the patient is
allergic to the implant,
four weeks prior to the
treatment.
Collagen
is manufactured under many
names, two of which are
Zyderm and Zyplast.
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Collagen can
be injected under the skin
to fill lines and wrinkles.
It is also used for lip
enhancement.
The
treatment takes less than
an hour. |
Redness and
swelling may occur.
Allergic reactions are
possible in 3-4% of
patients. |
The effect
normally lasts for three to
four months. |
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Stabilized Non-Animal
Hyaluronic acid gel (NASHA) |
Hyaluronic
acid is a substance that
exists naturally in the
body. Its most important
function is to carry and
bind water. Non-animal,
stabilized hyaluronic acid
(NASHA) does not contain
animal protein and does not
require a skin test prior
to treatment.
NASHA is
a unique form of hyaluronic
acid, manufactured under
the name of RESTYLANE.
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RESTYLANE is
designed for different
purposes and effects, from
reducing wrinkles and folds
to enhancing facial
contours and sculpting
lips. The treatment often
takes less than half an
hour. |
Injection-related adverse
reactions such as swelling,
redness and tenderness
might occur. Other adverse
reactions are very rare. |
The result
is immediate and can last
from 6 - 12 months,
depending on the patient
and the area that is being
treated.
Wrinkle
treatment tends to last
from 6 - 12 months and lip
enhancement for around 6
months. |
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Other Hyaluronic acid
products |
In addition
to RESTYLANE, a range of
hyaluronic acid treatments
is available. Some of these
products are derived from
cockscombs bred especially
for this purpose.
Hyaluronic acid is
manufactured under the
names of Hylaform,
Juvederm, Rofilan and
AcHyal. |
Hyaluronic
acid is used to treat lips,
wrinkles and facial lines.
The treatment takes less
than an hour to perform.
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Swelling,
redness and tenderness may
occur at the site of
injection. |
The duration
varies depending on the
type of product, the
condition of the patient
and the area being treated. |
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Permanent/semi-permanent
skin implants |
Permanent
and semi-permanent skin
implants contain a range of
different synthetic
ingredients to make the
product last longer.
Permanent
and semi-permanent skin
implants are manufactured
under the names of Artecoll,
Dermalive, NewFill,
Evolution, Outline and
Amazingel.
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These
products are used to fill
lines and wrinkles and to
augment lips by injection.
Some of the products
require at least two
treatment sessions.
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For some of
the products, very little
or no safety data at all
are available. Immediate
reactions include redness
and swelling at the
injection site. Longer-term
reactions are also known to
occur over time. They
include permanent redness,
inflammation, lumpiness,
skin discoloration or
granulomas. |
The duration
differs between the
products. Some claim to
last for ever, while others
offer a sustained
improvement for up to
twelve months. |
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Fat
injections / liposculpture |
Fat injections or
liposculpture are performed
using the patient's own fat
cells (autologous fat)
taken from unwanted fat
deposits. There are many
variables in this
treatment, including the
way the fat is extracted,
whether frozen or fresh fat
is used, the area that is
injected, the amount of fat
that is used and how deeply
the fat is injected. |
The fat is
injected under the skin to
treat hollow cheeks, to
enhance lips or cheeks or
to treat deep folds. The
procedure is performed
under local anaesthesia and
can take from less than one
hour to several hours. |
Some
lumpiness can occur, in
addition to
injection-related
reactions. If the patient
puts on weight, the
injected area can become
enlarged, which may not be
desirable. |
The reported
duration varies from a few
months to several
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Restylane Injections
Restylane®
is a cosmetic dermal filler made of
hyaluronic acid, a natural substance
that already exists in the human
body. The hyaluronic acid in
Restylane
is a crystal-clear gel called NASHA™
or Non-Animal Stabilized Hyaluronic
Acid. NASHA is completely
biocompatible with human hyaluronic
acid.
Restylane
maintains its shape using the body's
own moisture. The hyaluronic acid in
Restylane
is hydrophilic or "water loving." As
hyaluronic acid gradually degrades,
each molecule binds to more water and
over time, the same volume can be
maintained with less hyaluronic acid.
This ability of hyaluronic acid to
bind to water is what helps provide
lasting results.
Unlike rooster-derived hyaluronic
acids and bovine collagen products,
Restylane
is free from animal proteins. This
limits any risk of animal-based
disease transmissions or development
of allergic reactions to animal
proteins.*
Restylane is primarily used for lip
enhancement (especially to prevent
lipstick “bleeding”) and wrinkle
correction. Performed in 30-minute
sessions, Restylane treatments are
long lasting and can be repeated as
necessary, typically every six to 12
months.
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